Niacin Supreme

Each 2 capsules contain:
Niacin (inositol hexanicotinate 1,000 mg
Vitamin B-6 50mcg
Folic Acid 400 mcg
Vitamin B-12 100 mcg
Chromium (arginate)
Inositol (inositol hexanicotinate) 150mg
Other ingredients: silicon dioxide, gelatin, water

* NIACIN HAS DEMONSTRATED BETTER OVERALL RESULTS THAN CHOLESTEROL-LOWERING AGENTS IN REDUCING THE RISK OF CORONARY DEATH DISEASE

* NIACIN WAS THE ONLY CHOLESTEROL-LOWERING AGENT FOUND TO REDUCE THE DEATH RATE IN THE CORONARY DRUG PROJECT

* BECAUSE OF ITS LOW COST AND PROVEN EFFICACY, NIACIN SHOULD BE CONSIDERED THE FIRST CHOLESTEROL-LOWERING AGENT TO TRY.

* THE PROBLEMS WITH NIACIN (e.g. skin flushing, other side effects and patient compliance) CAN BE AVOIDED BY USIING INOSITOL HEXANIACINATE.

* SUSTAINED RELEASE NIACIN SHOULD NOT BE USED DUE TO GREATER TOXICITY IN THE LIVER.

Despite the fact that niacin has demonstrated better overall results than other cholesterol-lowering agents in reducing the risk of coronary heart disease, physicians are often reluctant to prescribe niacin. Several of the cholesterol-lowering drugs are actually associated with an increase in noncardiovascular mortality. Cholesterol-lowering drugs are toxic to the liver and extremely carcinogenic (cancer-causinig).

The cholesterol lowering activity of niacin was first described in the 1950s. It is now know that niacin does much more than lower the total cholesterol level. Specifically, niacin has been shown to lower LDL cholesterol, Lp(a), triglyceride, and fibrinogen (a blood protein that causes clot formation)levels, while raising HDL cholesterol levels.

In 1994, the Annals of Internal Medicine published the first clinical study that directly compared niacin and lovastatin. The results indicated that, while lovastatin produced a greater reduction in LDL cholesterol levels, niacin provided better overall results despite the fact that fewer patients were able to tolerate a full dosage of niacin because of skin flushing. The percentage increase in HDL cholesterol, a more significant indicator for coronary heart disease, was dramatically in favor of niacin (330% vs 7%). Equally impressive was the percentage decrease in Lp(s) level.

The safest form of niacin at present is known as inositol hexaniacinate. This form of niacin has long been used in Europe to lower cholesterol levels and to improve blood flow in cases of intermittent claudication. It yields slightly better results than standard niacin but is much better tolerated, both in terms of flushing and, more important, long-term side effects.

Because of its low cost and proven efficacy, niacin should be considered the first cholesterol-lowering agent to try. The problems with niacin (skin flushing and other side effects) can be avoided by using inositol hexaniacinate. Sustained-release niacin should not be used.

Dosage

For Niacin Supreme, begin with 500 mg three times per day for two weeks, then increase to 1,000 mg. It is best to take Niacin Supreme with meals.

The information presented here is meant only to be educational in nature. The statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.